Factors Influencing the Optimal Control-to-Case Ratio in Matched Case-Control Studies
نویسندگان
چکیده
منابع مشابه
Matched Case-Control Studies
'National Cancer Institute, Biometric Research Branch, DCTD, Executive Plaza North, Room 739, 6130 Executive Boulevard, MSC 7434, Bethesda, Maryland 20892-7434, U.S.A. 2National Cancer Institute, Biometry Research Group, DCP, Executive Plaza North, Room 344, 6130 Executive Boulevard, Bethesda, Maryland 20892, U.S.A. 3F0x Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, Pennsylvania 1911...
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Multiple control groups in case-control studies are used to control for different sources of confounding. For example, cases can be contrasted with matched controls to adjust for multiple genetic or unknown lifestyle factors and simultaneously contrasted with an unmatched population-based control group. Inclusion of different control groups for a single exposure analysis yields several estimate...
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There are two common misconceptions about case-control studies: that matching in itself eliminates (controls) confounding by the matching factors, and that if matching has been performed, then a “matched analysis” is required. However, matching in a case-control study does not control for confounding by the matching factors; in fact it can introduce confounding by the matching factors even when...
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Case-control studies occupy a central place in epidemiological research. The basic idea here is the comparison of a group (the “cases”) having the outcome of interest (normally some disease) with respect to a control group (those without disease) regarding one or more characteristics (exposure to certain external events). One of the early examples, which sparked a lot of debate in the fifties b...
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Power calculations are derived for matched case-control studies in terms of the probability po of exposure among the control patients, the correlation coefficient phi for exposure between matched case and control patients, and the odds ratio psi for exposure in case and control patients. For given Type I and Type II error probabilities alpha and beta, the odds ratio that can be detected with a ...
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ژورنال
عنوان ژورنال: American Journal of Epidemiology
سال: 1999
ISSN: 0002-9262,1476-6256
DOI: 10.1093/oxfordjournals.aje.a009786